Product Highlight

NIKKOL LECINOL® MFL: a neurocosmetic approach to regulating skin hyperinnervation

Product HighlightBeauty & Personal Care

Targeting the skin–nerve connection to support sensitive skin and barrier resilience

Why choose NIKKOL LECINOL® MFL?

Skin sensitivity goes beyond a weakened barrier. Altered cutaneous innervation and excessive nerve fibre elongation can contribute to heightened skin reactivity, discomfort and itch.
NIKKOL LECINOL® MFL is a multifunctional lysolecithin containing lysophosphatidic acid (LPA) as its active component. Its distinctive neurocosmetic approach targets cutaneous nerve regulation, while simultaneously strengthening the skin barrier.

INCI: Lysolecithin

Key benefits

  • Neurocosmetic action: supports the regulation of cutaneous innervation through the LPA–Semaphorin 3A pathway
  • Helps reduce skin sensitivity and reactivity by regulating excessive nerve elongation
  • Strengthens the skin barrier by promoting epidermal differentiation, boosting filaggrin and supporting ceramide synthesis
  • Helps reduce inflammation associated with external stimuli
  • Improves hydration, TEWL, redness and skin roughness

How to use in formulation

  • Recommended use level: 0.1-0.2%
  • Recommended pH: 5-8
  • Suitable for hot and cold processes. For hot processing, dissolve in the water phase at approximately 40°C and add towards the end of the process. For cold processing, disperse thoroughly in the water phase. Avoid prolonged heating and consider adding tocopherol as an antioxidant.


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NIKKOL LECINOL® MFL: a neurocosmetic approach to regulating skin hyperinnervation | IMCD South Africa